Thapsigargin | SERCA ATPase Inhibitor | Tocris Bioscience
HRC promotes anoikis resistance and metastasis by suppressing endoplasmic reticulum stress in hepatocellular carcinoma
What is Thapsigargin? Frequently Asked Questions
Pancreatic INS-1 β-Cell Response to Thapsigargin and Rotenone: A Comparative Proteomics Analysis Uncovers Key Pathways of β-Cell Dysfunction | Chemical Research in Toxicology
Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components | Cell Communication and Signaling | Full Text
Thapsigargin promotes colorectal cancer cell migration through upregulation of lncRNA MALAT1
Diabetes Alters Intracellular Calcium Transients in Cardiac Endothelial Cells | PLOS ONE
MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System | eNeuro
Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1 | Aging
Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation | Journal of Experimental & Clinical Cancer Research | Full Text
IJMS | Free Full-Text | Valproate Attenuates Endoplasmic Reticulum Stress-Induced Apoptosis in SH-SY5Y Cells via the AKT/GSK3β Signaling Pathway
Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway - ScienceDirect
Endoplasmic reticulum stress signalling – from basic mechanisms to clinical applications - Almanza - 2019 - The FEBS Journal - Wiley Online Library
Proteomic Signatures in Thapsigargin-Treated Hepatoma Cells | Chemical Research in Toxicology
Effect of endoplasmic reticulum calcium on paraquat‑induced apoptosis of human lung type II alveolar epithelial A549 cells
Frontiers | STING, the Endoplasmic Reticulum, and Mitochondria: Is Three a Crowd or a Conversation?
IJMS | Free Full-Text | Thapsigargin—From Traditional Medicine to Anticancer Drug
Endoplasmic reticulum stress stimulates the release of extracellular vesicles carrying danger-associated molecular pattern (DAMP) molecules | Oncotarget
SEC24A identified as an essential mediator of thapsigargin-induced cell death in a genome-wide CRISPR/Cas9 screen | Cell Death Discovery
Knocking out the door to tunicamycin entry | PNAS
Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4–CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA | Journal of Neuroscience
Kinetics of Thapsigargin- Ca2+-ATPase (Sarcoplasmic Reticulum) Interaction Reveals a Two-step Binding Mechanism and Picomolar Inhibition * - Journal of Biological Chemistry
Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation: Molecular Therapy - Oncolytics
Luteolin prevents liver from tunicamycin-induced endoplasmic reticulum stress via nuclear factor erythroid 2-related factor 2-dependent sestrin 2 induction - ScienceDirect
Molecules | Free Full-Text | Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics
Thapsigargin sensitizes human esophageal cancer to TRAIL-induced apoptosis via AMPK activation | Scientific Reports
